Human Dipeptidyl peptidase 1 (CTSC) ELISA Kit

A Sandwich ELISA kit from Assay Genie is intended for the quantitative measurement of human Dipeptidyl peptidase 1 (CTSC) in research samples. The assay is reactive with human samples and accepts serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. It demonstrates a detection range of 0.312-20ng/mL and a sensitivity of 0.12ng/mL, with intra-assay CV of 6.3% and inter-assay CV of 9.2%. The kit specifically detects natural and recombinant human Dipeptidyl peptidase 1.

The target protein, also known as Cathepsin C, Cathepsin J, Dipeptidyl peptidase I, Dipeptidyl transferase, DPP-I, or CPPI, is a lysosomal thiol protease with dipeptidylpeptidase activity. It can act as both an exopeptidase and endopeptidase, and activates serine proteases such as elastase, cathepsin G, and granzymes A and B, as well as neuraminidase and factor XIII. Dysregulation of CTSC has been linked to cancer, immune disorders, and inflammatory conditions, making it a potential biomarker for disease diagnosis and treatment development. Research applications include signal transduction, and the protein is associated with Papillon-Lefevre syndrome, Haim-Munk syndrome, and aggressive periodontitis type 1. For research use only.