Human Dihydropyrimidinase-related protein 2 (DPYSL2) ELISA Kit

A high-quality Sandwich ELISA Kit from Assay Genie designed for the accurate quantification of human Dihydropyrimidinase-related protein 2 (DPYSL2) in human samples. The assay is reactive with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids and uses a colorimetric detection method.

DPYSL2, also known as collapsin response mediator protein 2 (CRMP2), plays a role in neuronal development and polarity, axon growth and guidance, neuronal growth cone collapse and cell migration, and is necessary for signaling by class 3 semaphorins. Dysregulation of DPYSL2 has been linked to neurodevelopmental and neurodegenerative disorders, making it a valuable biomarker in neuroscience research. The kit recognises natural and recombinant human DPYSL2, with a detection range of 0.312-20ng/mL, a sensitivity of 0.156ng/mL, an intra-assay CV of 4.2% and an inter-assay CV of 5.6%.

Linearity has been validated across serum, EDTA plasma and heparin plasma samples, with recovery of 85% (range 80-91%) in serum and 87% (range 81-93%) in plasma. The kit is intended for research use only within the neurosciences field.