Human Dexamethasone-induced protein (DEXI) ELISA Kit

Assay Genie offers a Sandwich ELISA Kit designed for the accurate measurement of Dexamethasone-induced protein (DEXI) levels in human serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. The kit provides high sensitivity and specificity, ensuring precise and reproducible results suitable for a range of research applications, and uses a colorimetric detection method.

DEXI is induced by dexamethasone, a synthetic glucocorticoid commonly used in anti-inflammatory and immunosuppressive therapies. The protein plays a role in modulating immune responses and inflammatory processes, making it a valuable biomarker for studying immune-related disorders such as autoimmune diseases and chronic inflammation. The assay shows specificity for natural and recombinant human DEXI and is intended for research use only.

Reported performance characteristics include a detection range of 0.78-50ng/ml and a sensitivity of 0.34ng/mL, with an intra-assay CV of 6.5% and inter-assay CV of 7.6%. Linearity has been established for serum, EDTA plasma, and heparin plasma across serial dilutions, and recovery is 95% (range 89-101%) for serum and 97% (range 91-103%) for plasma. The kit targets DEXI (UniProt O95424, NCBI Gene ID 28955), also known as Protein MYLE, with a molecular weight of 10,429 Da.