Human Desmocollin-2 PharmaGenie ELISA Kit (SBRS0509)

This PharmaGenie-format ELISA from Assay Genie targets the human Desmocollin-2 cadherin encoded at chromosomal locus 18q12.1, also referenced under the synonyms ARVD11, CDHF2, DG2, DGII/III, and Cadherin family member 2 (UniProt Q02487). The capture antibody is human-specific, and the manufacturer reports no significant cross-reactivity with mouse or rat DSC2 orthologs, which makes the plate well suited to studies of patient-derived endomyocardial biopsies, primary keratinocyte monolayers, and stratified carcinoma cohorts where species-matched quantitation is critical for biomarker interpretation.

For orthogonal validation, the kit pairs cleanly with semi-quantitative western blot and immunohistochemistry workflows that confirm DSC2 localization at cardiomyocyte intercalated discs and at epidermal desmosomal plaques, enabling cross-platform correlation of ectodomain-shedding fragments against full-length cadherin levels in the same samples. Each kit ships with a 12-month shelf life when refrigerated at 2 to 8 °C; reconstituted standards should be aliquoted into single-use vials and stored frozen to limit freeze-thaw cycles, while prepared wash buffer and 1X assay diluent remain stable at room temperature during the run.