Human Dermatan Sulfate Epimerase (DSE) ELISA Kit

The Assay Genie Human Dermatan Sulfate Epimerase (DSE) ELISA Kit enables quantitative measurement of DSE, the enzyme that catalyzes the epimerization of D-glucuronic acid to L-iduronic acid during glycosaminoglycan biosynthesis. The kit includes pre-coated plates, detection antibodies, and standard reagents sufficient for one microplate run. Researchers can profile DSE expression across experimental conditions using prepared tissue homogenates or cell lysates. The standard protocol calls for a 100 µL sample volume per well, with absorbance recorded after substrate addition. Store reagents at 4°C to preserve stability; the kit is intended for research use only. The assay is suited to studies of connective tissue disorders, including musculocontractural Ehlers-Danlos syndrome, where DSE mutations have been documented.