Human Deoxyribonuclease I Like Protein 3 ELISA Kit

A microplate-based colorimetric platform from Assay Genie supports quantitative measurement of DNASE1L3 in research workflows focused on nuclease biology, autoimmune disease, and chromatin clearance. The Human Deoxyribonuclease I Like Protein 3 ELISA Kit addresses an endonuclease responsible for chromatin fragmentation during programmed cell death and for clearance of cell-free DNA; loss-of-function mutations are strongly associated with monogenic systemic lupus erythematosus and hypocomplementemia, making accurate quantification a valuable translational endpoint.

The kit supplies sufficient reagents for 96 individual determinations and supports measurement across tissue homogenates and common blood-derived research specimen types. The established in vitro immunoassay workflow accommodates medium-throughput experimental designs and clinical cohort screening. Applications include evaluation of macrophage or dendritic cell function, profiling of drug candidates that modulate DNA clearance, and analysis of patient-derived samples in rheumatology research.

Quality-controlled components arrive with a complete buffer set, supporting reproducible performance across runs. Standard laboratory equipment including a microplate reader is required for absorbance data acquisition. Intended for research use only; not validated for diagnostic procedures.