Human DEGS1 (Sphingolipid delta (4)-desaturase DES1) ELISA Kit (HUFI05315)

DEGS1 encodes the delta(4)-desaturase DES1 enzyme, which catalyzes the final step in de novo ceramide biosynthesis by inserting a double bond into dihydroceramide. The protein is anchored in the endoplasmic reticulum membrane and operates through an electron transfer chain involving cytochrome b5 and molecular oxygen. Aberrant DEGS1 activity has been linked to metabolic dysfunction, neurodegeneration, and tumor progression, making quantitative protein measurement increasingly relevant in lipid signaling research. The Assay Genie kit supports reproducible quantification of human DEGS1, advancing studies of sphingolipid pathway dysregulation, insulin resistance, and inflammatory conditions. Laboratory recommendations include aliquoting reagents and limiting freeze-thaw cycles to preserve antibody binding performance. For research use only; not intended for diagnostic or therapeutic applications.