Human Cytokeratin 18/KRT18 PharmaGenie ELISA Kit (SBRS0482)

Cytokeratin 18 (KRT18) is a 45 kDa type I intermediate filament protein expressed in epithelial-derived cells and widely used as a biomarker in epithelial biology and pathology research. This quantitative immunoassay from Assay Genie enables researchers to measure soluble KRT18 released from epithelial cells and hepatocytes into cell culture supernatants and blood-derived samples. Elevated circulating levels of KRT18 and its caspase-cleaved fragment, including the M30 antigen, are studied as indicators of hepatocyte injury, tumor cell death, and epithelial barrier disruption in cancer, liver disease, and toxicology studies. The kit is configured for 96 assays and is intended for research use only, supporting pharmacogenomic and biomarker discovery workflows that require reproducible quantification across multiple samples. Each kit provides the essential reagents, coated plate, and standards needed to run the assay, with absorbance readout on a standard microplate reader.