Human Cytochrome P450 Reductase (CPR) ELISA Kit

The diflavin enzyme cytochrome P450 reductase (CPR, also known as POR or P450 oxidoreductase) transfers electrons to microsomal cytochrome P450 monooxygenases, the principal system for hepatic and extrahepatic metabolism of drugs, steroids, fatty acids, and environmental xenobiotics. Quantifying CPR protein abundance is essential for pharmacokinetic research, toxicology studies, and investigation of POR polymorphisms linked to altered drug response, Antley-Bixler syndrome, and steroidogenesis disorders.

This colorimetric immunoassay kit from Assay Genie is supplied in a 96-assay format and validated for human tissue homogenates and cell lysates. The assay enables researchers to measure CPR levels across in vitro and in vivo experimental models, supporting drug metabolism studies, enzyme induction assays, and personalized medicine workflows where microsomal P450 activity drives therapeutic outcomes and adverse-effect profiles.