Human Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) ELISA Kit

The CFTR gene encodes a cAMP-regulated chloride channel located in the apical membrane of epithelial cells that line the airways, pancreas, intestines, and other mucosal surfaces. Loss-of-function mutations in this channel disrupt anion transport and fluid homeostasis, producing the pathology investigated in cystic fibrosis research. This immunoassay from Assay Genie is calibrated against the human CFTR protein and supports laboratory work in pulmonary biology, epithelial-cell physiology, and translational studies of mutant channel rescue.

The kit supplies reagents sufficient for a full microplate of quantitative determinations. Prepared cell lysates and tissue homogenates are the intended starting material, and the assay fits projects measuring relative CFTR abundance, comparing wild-type and mutant protein levels, or following changes after candidate corrector or potentiator compound treatment in cell culture models. Researchers should refer to the protocol insert for reagent preparation, suggested dilution ranges, and plate-reader setup.

For research use only; not intended for clinical or diagnostic applications. Storage and handling should follow the conditions stated in the product documentation.