Human Cystatin C PharmaGenie ELISA Kit (SBRS0476)

This colorimetric immunoassay from Assay Genie measures human Cystatin C, a low-molecular-weight (~13 kDa) cysteine protease inhibitor encoded by the CST3 gene and produced constitutively by all nucleated cells. Because circulating Cystatin C is freely filtered by the renal glomerulus and fully catabolized by proximal tubule cells, blood concentrations serve as an early indicator of glomerular filtration rate (GFR) and a sensitive marker that often responds ahead of creatinine in declining renal function. The assay is specific to human Cystatin C and has been validated for cell culture supernatants and clinical sample types including plasma and serum, supporting translational research in nephrology, cardiovascular risk stratification, diabetic kidney disease, and neurodegenerative studies where altered Cystatin C concentrations have been reported. The 96-assay microplate format delivers a colorimetric readout on standard laboratory plate readers, with all required reagents supplied for the complete protocol, including pre-coated plate, detection antibody, calibrator standards, and substrate. Reconstituted reagents and unused strips should be stored according to the protocol insert to preserve activity. Intended for research use only.