Human Cystathionine Gamma Lyase (CSE) ELISA Kit

Cystathionine gamma-lyase (CSE), encoded by the CTH gene, catalyzes the final step of the transsulfuration pathway, converting cystathionine into cysteine, ammonia, and 2-oxobutanoate while contributing to endogenous hydrogen sulfide (H2S) production. Investigators studying H2S signaling, cardiovascular physiology, and hepatic sulfur metabolism rely on quantitative measurement of CSE protein in human-derived specimens. The Assay Genie Human CSE ELISA Kit delivers quantitative detection in tissue homogenates, cell lysates, and related human sample matrices, enabling comparison of expression across treatment groups, patient cohorts, and disease models. Each kit provides reagents for 96 reactions in a microplate format and uses an absorbance-based readout compatible with standard plate readers. Pre-coated wells capture analyte from standards and samples, with detection via enzyme-conjugated secondary antibody, chromogenic substrate development, and stop solution. Researchers investigating cystathionine pathway flux, redox biology, or pharmacological inhibition of H2S synthesis use this kit to track CSE levels following genetic knockdown, small-molecule inhibitor exposure, or in vitro stimulation of cultured cells.