Human Cyclin-dependent kinase 5 (CDK5) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the precise measurement of human Cyclin-dependent kinase 5 (CDK5) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, using a colorimetric detection method. The kit is specific for both natural and recombinant human Cyclin-dependent-like kinase 5 and offers a detection range of 0.312-20ng/mL with a reported sensitivity of 0.1ng/mL. Reported precision values are an intra-assay CV of 6.1% and an inter-assay CV of 9.3%.

CDK5 is a proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation, with roles in neuronal survival, migration, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission. Dysregulation of the kinase has been linked to neurodegenerative diseases such as Alzheimer's and Parkinson's, as well as various cancers, making it a valuable biomarker for research into these conditions and for investigating potential therapeutic interventions.