
Human CTNND1 (Catenin delta-1) ELISA KIT (HUFI08228)
Price on request
| SKU | Price | Quantity |
|---|---|---|
| HUFI08228 | Price on request |
Description
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This colorimetric immunoassay kit from Assay Genie enables quantification of Catenin delta-1 (CTNND1), the p120-catenin armadillo-repeat protein that stabilizes the cadherin-catenin complex at epithelial adherens junctions. CTNND1 governs E-cadherin endocytic trafficking, modulates RhoA and Rac1 GTPase activity at the plasma membrane, and shuttles between junctional, cytoplasmic, and nuclear pools where it influences Kaiso-mediated transcription. Its misexpression and isoform switching are recurrent findings in breast, prostate, gastric, colorectal, and head-and-neck carcinomas.
Packaged in a 96 Assays format with all reagents supplied ready-to-use, the kit accommodates standard curve generation alongside unknown samples. Researchers investigating epithelial-mesenchymal transition, tumor invasion mechanisms, Wnt-pathway cross-talk, or circulating biomarker discovery can apply the assay to clarified human serum or plasma. The colorimetric endpoint is read on standard microplate readers. Unopened kits should be refrigerated; reconstituted components are stored frozen at -20 °C for longer-term use. For research use only.
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