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Human CRY alphaB (Crystallin Alpha B) ELISA Kit (HUES02541)
  • Human CRY alphaB (Crystallin Alpha B) ELISA Kit (HUES02541)
Assay Genie

Human CRY alphaB (Crystallin Alpha B) ELISA Kit (HUES02541)

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HUES02541

Price on request

Description

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Crystallin alphaB (CRYAB, also called HSPB5) is a 20 kDa small heat shock protein that acts as a molecular chaperone, holding partially folded substrates in a folding-competent state under cellular stress. Quantifying this chaperone in human specimens supports ophthalmology, neuromuscular disease, and oncology research, where CRYAB dysregulation has been linked to cataracts, myofibrillar myopathy, dilated cardiomyopathy, and certain solid tumours.

This quantitative immunoassay from Assay Genie measures endogenous CRYAB using an absorbance-based end-point readout. Reagents are supplied for 96 assays in a microplate workflow that fits mid-throughput screening of patient cohorts, tissue lysates, or conditioned media. Pre-coated plate wells and the accompanying buffer set are provided so laboratories can apply the kit directly to retinal, cardiac, or tumour-tissue studies investigating oxidative stress, heat-shock responses, and therapeutic intervention.

The kit is intended for research use only and is compatible with cell-culture supernatants, tissue homogenates, and standard clinical sample preparations collected under investigator-approved protocols.