Human Cross-linked N-terminal telopeptide of Collagen alpha-1 (I)chain (INTX) ELISA Kit

From Assay Genie, this ELISA kit is intended for the quantitative measurement of Cross-linked N-terminal telopeptide of Collagen alpha-1 (I) chain (INTX), a biomarker used to assess the rate of bone turnover and collagen degradation. Employing a Sandwich assay format with reactivity for human samples, the kit supports research into bone metabolism and bone-related disorders such as osteoporosis and osteogenesis imperfecta. NTX can be measured in urine or serum.

The assay reports a detection range of 0.312-20ng/mL with a sensitivity of 0.15ng/mL. Intra-assay precision is 4.3% CV and inter-assay precision is 7.5% CV. Reported linearity for serum ranges from 86-120% across dilutions of 1:2 to 1:16; EDTA plasma 91-116%; heparin plasma 82-115%. Recovery in serum averages 96% (range 90-102%) and in plasma averages 98% (range 92-104%). Compatible sample types include serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids, with specificity for both natural and recombinant human Cross-linked N-terminal telopeptide of Collagen alpha-1 (I) chain. For research use only.