Human Cross Linked N-Telopeptide Of Type I Collagen (NTXI) ELISA Kit

Researchers studying bone turnover use this competitive ELISA from Assay Genie to quantify cross-linked N-telopeptide of type I collagen (NTX-I) in human samples. NTX-I is a small peptide fragment released into circulation when osteoclasts resorb bone matrix, and it serves as a circulating biomarker of bone resorption in studies of osteoporosis, metastatic bone disease, and metabolic bone disorders.

The kit is also relevant for monitoring responses to antiresorptive therapies such as bisphosphonates and denosumab, where serial NTX-I measurements can reflect changes in osteoclast activity over time. It is supplied in a microplate format with 96 assays per kit, validated for plasma, serum, and urine specimens, and read on a standard colorimetric plate reader. Intended for research use only, the assay supports investigation of postmenopausal bone loss, fracture risk, chronic kidney disease-related mineral disorders, and pediatric bone metabolism.