Human CRADD (Death domain-containing protein CRADD) ELISA KIT (HUFI05377)

CRADD, also called RAIDD (RIP-Associated ICH-1/Ced-3-homologous protein with a Death Domain), is a bifunctional adaptor that recruits procaspase-2 into the TNF-R1 signaling complex via its CARD and death domain modules, linking death receptor activation to caspase-driven apoptosis. This quantitative protein assay from Assay Genie is intended for research use only and supports studies into programmed cell death, neurodevelopmental disease biology, and inflammatory signaling pathways. The kit format provides the reagents required for ELISA-based measurement of CRADD in human samples, making it a useful tool for laboratories investigating caspase-2-dependent apoptosis, RIP1 kinase signaling, and the role of CRADD loss-of-function variants associated with non-syndromic intellectual disability. Refer to the package insert for recommended storage temperature and specific assay protocol.