Human Corticotropin Releasing Hormone (CRH) ELISA Kit

The Corticotropin Releasing Hormone (CRH) competitive immunoassay from Assay Genie enables quantitative measurement of human CRH in biological samples. CRH is a 41-amino acid neuropeptide secreted by the paraventricular nucleus of the hypothalamus that triggers the hypothalamic-pituitary-adrenal (HPA) stress axis by stimulating pituitary ACTH release, which in turn drives cortisol secretion from the adrenal cortex. Altered CRH signaling has been linked in published research to anxiety disorders, major depressive disorder, post-traumatic stress, and chronic inflammatory conditions, supporting the value of accurate CRH quantitation in neuroendocrine studies. This research use only kit is supplied as a pack of 96 assays, with all components required to run a quantitative binding assay in a microplate format. Investigators studying the HPA axis, stress biology, or neuropeptide regulation can use the assay to examine circulating CRH concentrations in human cohorts and explore mechanistic links between central stress pathways and peripheral hormone output.