Human Corin (CRN) ELISA Kit

Corin is a transmembrane serine protease encoded by the CORIN gene and expressed predominantly in cardiomyocytes, where it cleaves pro-atrial natriuretic peptide (pro-ANP) into the biologically active hormone that governs sodium excretion and blood pressure regulation. The Assay Genie Human Corin (CRN) ELISA Kit is intended for quantitative measurement of circulating Corin in human specimens, supporting cardiovascular research into heart failure pathophysiology, hypertensive cardiac remodeling, preeclampsia biomarker discovery, and natriuretic peptide processing.

Research teams studying left ventricular dysfunction, hypertensive remodeling, and pregnancy-related cardiovascular complications use circulating Corin levels as a candidate biomarker tied to ANP pathway activity. The kit supports a range of specimen matrices including blood-derived fractions and tissue homogenates, making it adaptable to clinical cohort studies and preclinical models that probe Corin expression in cardiac tissue.

Each kit supplies reagents sufficient for 96 assays in a microplate format with a colorimetric readout for standard laboratory plate readers. The assay is configured for human reactivity, and investigators working with non-human specimens should validate sample compatibility independently before drawing quantitative conclusions.