Human Copper-transporting ATPase 1 (ATP7A) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA kit is designed for the quantitative detection of human Copper-transporting ATPase 1 (ATP7A) in serum and plasma samples. ATP7A is a transmembrane protein that functions in copper transport across membranes and is associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome.

The kit provides a detection range of 0.156-10ng/mL with a sensitivity of 0.095ng/ml. It reports an intra-assay precision of 6.3% and an inter-assay precision of 8.5%. Specificity is reported for natural and recombinant human Copper-transporting ATPase 1. Validated sample matrices also include tissue homogenates, cell culture supernates and other biological fluids.

Aimed at the neurosciences research area, the product is intended for research use only and detects the protein encoded by the ATP7A gene (NCBI Gene ID: 538; UniProt: Q04656), also known by the synonyms Copper pump 1, Menkes disease-associated protein, MC1, and MNK.