Human Complement Component 1, Q Subcomponent Like Protein 1 (C1qL1) ELISA Kit

The Assay Genie human C1QL1 ELISA enables quantitative measurement of Complement C1q-like protein 1, a secreted glycoprotein of the C1q/TNF superfamily distinguished by its globular gC1q domain and collagen-like stalk. C1QL1 is highly enriched in central nervous system tissue, where it localizes to synapses and supports synaptic adhesion through binding to BAI family adhesion receptors on neurons. Because of this restricted tissue distribution, the kit is widely applied in neurodevelopmental, neuroimmunology, and complement-pathway research.

Configured for human reactivity, the assay accepts tissue homogenates, cell lysates, and conditioned media as input. A colorimetric readout yields absorbance values proportional to C1QL1 concentration, with capture and detection antibodies raised against recombinant human C1QL1 epitopes to discriminate the target from paralogs such as C1QL2 and C1QL3. Researchers studying synapse formation, neurodegenerative disease, or complement signaling cascades can use this kit to profile C1QL1 levels across experimental cohorts.

For reliable performance, equilibrate all reagents to room temperature before running the assay, and store the kit refrigerated at 4 degrees C when not in use. Aliquot reconstituted standards and detection antibody to minimize freeze-thaw cycles and preserve binding activity over multiple experiments.