Human Complement C5/C5 ELISA Kit

Quantitative immunoassay from Assay Genie for measuring complement component C5, a central cleavage target of the complement cascade that gives rise to the anaphylatoxin C5a and the C5b fragment initiating membrane attack complex assembly. The microplate-based kit supports research workflows investigating complement activation in immune-mediated and inflammatory disease models, including studies of transplant rejection, sepsis pathophysiology, autoimmune hemolysis, and rare disorders such as paroxysmal nocturnal hemoglobinuria where terminal pathway blockade is therapeutically relevant. Reagents are provided as a complete set comprising pre-coated wells, biotinylated detector antibody, streptavidin-HRP conjugate, and standardized calibrator, sized for 96 determinations run in parallel. Working reagents should be handled at refrigerated temperatures, with longer-term storage of unused aliquots held below -20 degrees C to preserve activity. Researchers evaluating complement consumption, deposition, or systemic activation status can pair this kit with downstream validation by Western blot or functional hemolytic assays to triangulate protein-level findings with pathway activity.