Human Coagulation factor XI (F11) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is intended for the precise quantitative measurement of Coagulation factor XI (F11) in human serum, plasma, and cell culture supernatants. Designed for research use only, it supports investigations into the blood coagulation cascade, hemostasis, and clot formation, where dysregulation of F11 has been implicated in various bleeding disorders and thrombotic conditions.

The assay uses a Sandwich ELISA format with a detection range of 0.78–50 ng/mL and a sensitivity of 0.22 ng/mL. Reported precision figures are an Intra CV of 4.2% and an Inter CV of 9.6%. The kit is also suitable for tissue homogenates and other biological fluids, with specificity for natural and recombinant human Coagulation factor XI. The target protein, factor XI, triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.