Human CLK1 (Dual specificity protein kinase CLK1) ELISA KIT (HUFI05350)

The Assay Genie immunoassay kit supports quantitative measurement of dual specificity protein kinase CLK1, a nuclear serine/arginine protein kinase that phosphorylates SR-family splicing factors and governs alternative pre-mRNA splice site selection in human cells.

CLK1 research applications include investigations into spliceosome assembly, nuclear speckle organization, cancer cell proliferation signaling, viral replication mechanisms (including influenza A and HIV-1), and neurodegenerative pathways such as tau exon 10 inclusion relevant to Alzheimer's disease models. The kinase is also a focus for medicinal chemistry efforts targeting small-molecule CLK inhibitors used in laboratory proof-of-concept studies.

Supplied as a 96 Assays research-use kit for trained laboratory personnel running standard ELISA workflows on human samples.