Human CLC PharmaGenie ELISA Kit (SBRS0427)

The Human CLC PharmaGenie ELISA Kit from Assay Genie quantitatively measures Cardiotrophin-Like Cytokine (CLCF1) in human samples, with specific reactivity to human CLCF1 and no significant cross-reactivity to mouse or rat homologs. CLCF1 is a secreted member of the interleukin-6 cytokine family that forms a heterodimer with CRLF1 and activates downstream JAK/STAT signaling through the gp130 receptor. This assay enables investigation of CLCF1 biology in neurodevelopment, thermoregulation, and inflammatory cascades, with relevance to conditions such as Cold-Induced Sweating Syndrome and Crisponi syndrome.

The microplate-based workflow accommodates cell culture supernatant specimens, serum-derived samples, and plasma-derived samples, supporting translational studies in neuroimmunology and cytokine receptor signaling. Researchers apply this kit to quantify neurotrophic activity, map CNTFRα receptor interactions, and characterize ligand-receptor binding in vitro. For research use only.