Human Claudin 3 (CLDN3) ELISA Kit

Claudin 3 (CLDN3) is a transmembrane tight junction protein that seals the paracellular space between adjacent epithelial cells, helping maintain tissue barrier integrity and selective permeability. Loss or dysregulation of CLDN3 has been linked to disrupted barrier function in inflammatory conditions and to tumor progression in several cancers, including ovarian, colorectal, and gastric carcinomas, making it a frequent target in oncology and epithelial biology research.

This in vitro quantitative immunoassay from Assay Genie is configured for the measurement of human CLDN3 across multiple sample matrices, supporting studies of tight junction biology, epithelial-mesenchymal transition, and tumor marker discovery. The kit is supplied in a 96 assays plate format and is intended for research use only, not for diagnostic procedures.

Typical applications include profiling CLDN3 levels in patient-derived tissue homogenates, characterizing epithelial barrier models, screening drug candidates that modulate tight junction permeability, and investigating CLDN3 as a candidate biomarker in gastrointestinal and reproductive system cancers. Researchers studying inflammatory bowel disease, renal epithelial transport, and endometriosis also use CLDN3 quantification to monitor changes in junctional integrity under experimental conditions.