Human Claudin 11 (CLDN11) ELISA Kit

Claudin 11 (CLDN11) is a transmembrane tight junction protein critical to myelin sheath integrity in the central nervous system and to the blood-testis barrier in male reproductive tissue. The Assay Genie CLDN11 immunoassay is configured for quantitative measurement of this protein in human specimens. Researchers studying demyelinating disorders, oligodendrocyte biology, spermatogenesis, or testicular immunology use this ELISA platform to profile CLDN11 levels across experimental conditions. The assay supports a range of human specimen inputs, including whole-blood derivatives and tissue lysates, expanding its applicability to both clinical and preclinical sample archives. Each kit provides reagents sufficient for 96 determinations in a microplate format, enabling moderate-throughput screening. CLDN11 expression is frequently investigated in the context of multiple sclerosis, experimental autoimmune encephalomyelitis, and male infertility research, where altered tight junction function contributes to disease pathology. The colourimetric read-out produces a measurable signal proportional to CLDN11 concentration in the specimen, allowing standard curve-based quantification. Reagents should be kept refrigerated upon arrival and protected from light to preserve antibody binding activity until first use. The kit is supplied as a box of components for the plate-based workflow and is for research use only.