Human Cholinergic Receptor, Nicotinic, Alpha 7 (CHRNa7) ELISA Kit

About the CHRNA7 Target

The CHRNA7 gene encodes the alpha-7 nicotinic acetylcholine receptor (α7 nAChR), a homopentameric ligand-gated ion channel permeable to calcium ions. This receptor modulates cholinergic anti-inflammatory signaling, cognitive function, and synaptic plasticity, making it a central focus of research into Alzheimer's disease, schizophrenia, and neuroinflammation. The Assay Genie kit provides quantitative measurement of human α7 nAChR in tissue homogenates, cell lysates, and other biological preparations for in vitro research applications.

Kit Details and Practical Use

Built on a microplate-based capture-and-detection antibody format, the assay produces an enzyme-substrate based signal read on a standard plate reader. Researchers working with neuronal cell lines, primary microglia, or peripheral immune cells can apply cell lysates and tissue preparations directly. Unused strip wells should be resealed with the desiccant pouch and refrigerated to preserve antibody activity. The kit is intended for research use only and is not validated for diagnostic or clinical decision-making.