Human Choline kinase alpha (CHKA) ELISA Kit

Designed for the precise measurement of Choline kinase alpha (CHKA) levels, this Sandwich ELISA Kit from Assay Genie is intended for research use only. The assay is reactive with human samples, including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and shows specificity for natural and recombinant human Choline kinase alpha.

The kit delivers a detection range of 0.312-20ng/mL and a sensitivity of 0.18ng/mL, with intra-assay CV, inter-assay CV, linearity and recovery values provided with the kit. Synonyms for the target include CHETK-alpha, Ethanolamine kinase, EK, CK, CHK and CKI, and the protein is localised to the cytoplasm. The associated UniProt entry is P35790.

CHKA plays a key role in phospholipid biosynthesis and may contribute to tumor cell growth, catalysing the first step in phosphatidylcholine biosynthesis and also phosphorylating choline and ethanolamine, with higher activity towards choline. Dysregulation of CHKA has been linked to cancer, liver diseases and neurological disorders, making the kit a useful tool for research in cancer biology, metabolism and neuroscience.