Human CHEK2 (Serine/threonine-protein kinase Chk2) ELISA KIT (HUFI05363)

CHEK2 (Checkpoint Kinase 2) is a critical serine/threonine kinase in the DNA damage response pathway, activated by ATM following double-strand breaks and responsible for phosphorylating downstream effectors including p53, BRCA1, and CDC25 family members. The Assay Genie human CHEK2 ELISA kit enables quantitative measurement of total Chk2 protein levels in research samples, supporting investigations into genomic stability, hereditary cancer predisposition (notably Li-Fraumeni-related and BRCA-associated contexts), and cellular checkpoint signaling. The assay uses a colorimetric readout compatible with standard microplate readers. Each kit provides reagents sufficient for 96 determinations in a microplate format, with all buffers, plate, and detection components included for immediate use. Intended for research use only, supporting in vitro laboratory applications studying kinase expression, DDR pathway activity, and biomarker development in oncology and genotoxicity research.