Human CGRP-I PharmaGenie ELISA Kit (SBRS0016)

This competitive immunoassay from Assay Genie quantifies human Calcitonin Gene-Related Peptide I (CGRP-I), a 37-amino-acid neuropeptide implicated in trigeminovascular signaling, migraine pathogenesis, and neurogenic inflammation. The kit is configured for microplate-based workflows and accommodates up to 96 assays per run, supporting medium-throughput studies in vascular biology and neuroscience research.

CGRP-I is cleaved from the calcitonin gene-related peptide preproprotein and acts through the CLR/RAMP1 receptor complex to drive potent vasodilation. Researchers studying migraine models, cardiovascular signaling, or neuropeptide release kinetics use this kit to measure peptide levels in cell culture supernatants, as well as in human serum samples or plasma specimens.

The assay produces a colorimetric readout compatible with standard microplate readers. Each kit includes a pre-coated plate, detection reagents, and standards sufficient for quantitative analysis. Samples are processed at room temperature with standard incubation steps, and the resulting data support calculation of unknown concentrations against a standard curve.

Researchers evaluating trigeminal nerve activation, inflammatory mediators, or therapeutic candidates targeting CGRP signaling pathways rely on this reagent for reproducible peptide quantification. The kit is intended for research use only and is not validated for diagnostic procedures.