Human CFHR1 PharmaGenie ELISA Kit (SBRS0414)

The Human CFHR1 PharmaGenie ELISA Kit from Assay Genie enables quantitative measurement of Complement Factor H-Related Protein 1, a ~42 kDa plasma glycoprotein central to regulation of the alternative complement pathway. CFHR1 circulates in normal human serum at moderate concentrations and competes with complement factor H for surface and C3b binding sites, making its precise quantification valuable in studies of C3 glomerulopathy, atypical hemolytic uremic syndrome (aHUS), and age-related macular degeneration, where CFHR1 copy-number variation and autoantibody status both influence disease risk. Researchers apply this in vitro quantitative immunoassay to stratify patient cohorts, monitor complement dysregulation, and characterize genotype-phenotype relationships in the CFH/CFHR gene cluster. The capture antibody is human-specific, with no significant cross-reactivity observed with mouse or rat CFHR family members, supporting clean signal in human cohort studies. Each kit contains pre-coated microplate wells and the reagents required for the assay workflow, and components should be stored refrigerated between uses with limited freeze-thaw cycles to preserve antibody binding activity. The kit is configured for research use only and is intended for laboratory investigation of complement biology rather than diagnostic testing.