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Human CDCA8 (Cell division cycle-associated protein 8) ELISA Kit (HUFI03477)
  • Human CDCA8 (Cell division cycle-associated protein 8) ELISA Kit (HUFI03477)
Assay Genie

Human CDCA8 (Cell division cycle-associated protein 8) ELISA Kit (HUFI03477)

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HUFI03477

Price on request

Description

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CDCA8, also designated Borealin or DasraB, is a core subunit of the Chromosomal Passenger Complex that localizes to centromeres and the central spindle during mitosis, where it supports Aurora B kinase activity, corrects erroneous kinetochore-microtubule attachments, and ensures faithful cytokinesis. Aberrant CDCA8 expression has been linked to poor prognosis in non-small cell lung cancer, triple-negative breast cancer, gastric adenocarcinoma, and hepatocellular carcinoma, positioning the protein as a candidate biomarker for tumor burden and treatment monitoring studies. The Assay Genie kit is supplied as a complete set of pre-coated microwell strips, recombinant standards, detection antibodies, and assay buffers; unopened components should be refrigerated at 4 degrees C and protected from light. With a recommended 100 uL sample volume per well, investigators studying mitotic checkpoint failure, chromosomal instability, or proliferation indices apply this quantitative immunoassay for translational oncology workflows.