Human CD314 PharmaGenie ELISA Kit (SBRS0377)

Quantitative measurement of soluble CD314 (NKG2D/KLRK1) in human research specimens is supported by the Assay Genie Human CD314 PharmaGenie ELISA Kit, a colorimetric immunoassay developed for studies of innate immune activation. CD314 is a C-type lectin-like activating receptor expressed on natural killer cells, CD8+ cytotoxic T lymphocytes, and gamma-delta T cell subsets, where it engages stress-induced ligands such as MICA, MICB, and the ULBP family to drive cytotoxic responses against infected, transformed, or otherwise distressed cells. Investigators apply this kit to studies of tumor immune surveillance, viral pathogenesis, transplant immunology, and inflammatory disease monitoring, where circulating receptor concentrations serve as biomarkers of immune activation. The kit is validated for cell culture supernatant along with plasma and serum, accommodating both in vitro experimental work and clinical research workflows. Supplied in a microplate configuration sized for 96 assays per plate, the format supports medium-throughput screening of patient cohorts or treatment panels. Each kit contains pre-coated wells, biotinylated detection antibody, streptavidin-HRP conjugate, wash buffer, recombinant human CD314 reference standard, substrate solution, and stop reagent. Unopened components should be refrigerated upon arrival and protected from light to preserve reagent activity. This product is intended for research use only and is not validated for diagnostic procedures.