Human Cathepsin C PharmaGenie ELISA Kit (SBRS0353)

Cathepsin C (also known as dipeptidyl peptidase I, or DPPI) is a lysosomal cysteine protease that activates granule-associated serine proteases such as neutrophil elastase, cathepsin G, and granzymes in neutrophils, cytotoxic T lymphocytes, mast cells, and natural killer cells, placing it at the center of studies on innate immunity, inflammatory signaling, and protease cascade regulation. This PharmaGenie kit from Assay Genie supports quantitative measurement of human Cathepsin C in cell culture supernatants, plasma, and serum-derived samples, enabling research into neutrophil-mediated tissue damage, periodontal inflammation, and the inherited disorders Papillon-Lefevre syndrome and Haim-Munk syndrome, both of which are linked to loss-of-function mutations in the CTSC gene. The reagents are supplied in a microplate format complete with pre-coated wells, lyophilized standards, biotinylated detection antibodies, and streptavidin-HRP conjugate for in vitro research use only. Assay Genie provides a validated protocol optimized for routine laboratory workflows in immune cell biology, drug discovery, and biomarker development.