Human Catenin Beta 1 (CTNNb1) ELISA Kit

The β-catenin protein encoded by CTNNB1 is a central effector of canonical Wnt signaling and a structural component of adherens junctions, where it anchors E-cadherin to the actin cytoskeleton through α-catenin. Aberrant nuclear accumulation of β-catenin is a hallmark of Wnt-driven malignancies, most notably colorectal carcinoma and hepatocellular carcinoma, making quantitative measurement valuable for oncology research, developmental biology studies, and investigations of epithelial-mesenchymal transition.

Researchers commonly apply this Assay Genie kit to profile β-catenin levels in cell culture models, tumor xenograft lysates, and patient-derived specimens relevant to colorectal cancer, hepatocarcinogenesis, and stem cell differentiation workflows. The capture antibody specifically recognizes the human β-catenin sequence with no significant cross-reactivity with rodent orthologs, supporting clean quantification in xenograft and human cell line studies.

Each kit is supplied as a complete package with pre-coated microplate wells, detection antibody, recombinant protein standards, and substrate reagents in a single box of components intended for research use only. Store refrigerated at 4 °C and avoid repeated freeze-thaw cycles of reconstituted reagents to maintain assay performance.