Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit

The Human Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) ELISA Kit from Assay Genie quantifies adenosine deaminase 2 (ADA2), a secreted enzyme expressed predominantly by monocytes and macrophages. Research applications include investigating ADA2 deficiency (DADA2), a hereditary autoinflammatory disorder characterized by vasculitis, recurrent strokes, livedo racemosa, and combined immunodeficiency. Useful for clinical research on vascular inflammation, immune dysregulation, and the role of CECR1 in angiogenesis. The CECR1 gene maps to chromosome 22q11.2, a region implicated in cat eye syndrome and 22q11.2 deletion syndromes. Intended for research use only, the kit provides quantitative measurement for studies of myeloid cell function, vascular biomarker profiling, and inflammatory disease mechanisms.