Human Caspr2 PharmaGenie ELISA Kit (SBRS0350)

The Caspr2 (Contactin-associated protein-like 2) ELISA from Assay Genie is an in vitro research-use assay supporting quantitative measurement of human Caspr2 in cell culture supernatant, plasma, and serum specimens. Caspr2, encoded by the CNTNAP2 gene, is a transmembrane neuronal adhesion protein of the neurexin family that clusters at juxtaparanodes of myelinated axons and serves as a recognized autoantigen target in autoimmune encephalitis research, including limbic encephalitis, Morvan syndrome, and acquired neuromyotonia.

Configured in a 96 assay plate format with absorbance-based readout, the kit supports batched screening of clinical and experimental samples. Each kit includes pre-coated microplate wells, standards, detection reagents, and assay buffer sufficient to generate a complete standard curve, with results read on a standard microplate reader. The protocol is intended for research applications in anti-Caspr2 autoantibody-associated neurological disease, biomarker discovery, and characterization of neuronal autoimmunity pathways.

Investigators studying Caspr2 seropositivity, CNTNAP2-related disorders, or related neuroinflammation models can pair this kit with downstream flow cytometry, immunohistochemistry, and western blot workflows. Reagents should be handled per the package insert and stored at the temperature indicated by Assay Genie to preserve binding activity over the kit's shelf life.