Human Caspase 1 (CASP1) ELISA Kit

Quantitative measurement of human Caspase 1 (CASP1) protein is supported by this Assay Genie ELISA Kit, which serves researchers investigating inflammasome activation, IL-1β and IL-18 cytokine maturation, and pyroptotic cell death pathways in human-derived specimens. Caspase 1 is a cysteine-aspartic protease that processes pro-inflammatory cytokine precursors and mediates inflammatory responses, making accurate quantification valuable in studies of innate immunity, autoimmune disease models, and infectious disease research.

Each kit provides reagents for 96 individual assays and is compatible with sample matrices including tissue homogenates, cell lysates, and cell culture supernatants. The assay uses an absorbance-based readout on a standard microplate reader, and the protocol accommodates small sample volumes while supporting in vitro studies of stimulated immune cell cultures, including macrophages and monocytes. Researchers can compare CASP1 levels across experimental conditions such as pathogen challenge, drug treatment, or genetic manipulation to characterize inflammasome activity.

With reactivity specific to human samples, this kit is a practical tool for laboratories focused on inflammatory pathway research, drug discovery, and translational immunology studies.