Human Carnosine Dipeptidase-1/CNDP1 PharmaGenie ELISA Kit (SBRS0434)

CNDP1 encodes the secreted serum carnosinase that hydrolyses carnosine and related histidine-containing dipeptides, and quantitative measurement of circulating carnosinase supports research into diabetic nephropathy susceptibility linked to the CNDP1 (CTG)n repeat polymorphism. This immunoassay kit from Assay Genie is supplied as a complete set with pre-coated microplate wells, lyophilised recombinant standards, biotinylated detection antibody, streptavidin conjugate, and chromogenic substrate reagents sufficient for 96 determinations in a single run. The capture and detection antibodies are specific for human CNDP1, providing selective quantification of the secreted serum isoform with minimal cross-reactivity to the homologous cytosolic carnosinase CNDP2. Reagents are configured for research use only and are validated across a panel of specimen matrices relevant to clinical and metabolic research, including cultured cell supernatants and clinically collected biospecimens, supporting biomarker discovery, metabolic disease research, and investigations of carnosine homeostasis in cardiovascular and renal studies. Researchers should store unopened kit components refrigerated, allow reagents to equilibrate to room temperature before each run, and avoid repeated freeze-thaw cycles of reconstituted standards to preserve immunoreactivity.