Human Carboxypeptidase E (CPE) ELISA Kit

A quantitative immunoassay from Assay Genie designed for measuring human Carboxypeptidase E (CPE), a zinc-dependent metallocarboxypeptidase that performs C-terminal trimming of peptide hormone and neuropeptide precursors within the regulated secretory pathway. CPE activity is essential for the biosynthetic maturation of insulin, enkephalin, and many other bioactive peptides, and altered CPE expression has been documented in obesity, type 2 diabetes, Alzheimer's disease, and certain neuroendocrine tumors. This research-use-only kit supports in vitro quantification of CPE in tissue homogenates and cell lysates, serving endocrinology, neuroscience, and metabolic disease research workflows.

Each pack provides reagents sufficient for 96 assays, with a colorimetric readout compatible with standard microplate readers. The assay targets human CPE and is supplied as a complete kit format, allowing laboratories to profile carboxypeptidase levels across experimental conditions, cell models, and tissue preparations without the need for custom antibody pairing. Researchers investigating prohormone convertase activity, neuropeptide processing, granule packaging mechanisms, or CPE-related signaling pathways can use the kit to compare CPE abundance between healthy and diseased samples, or to track enzyme levels following pharmacological, genetic, or dietary interventions in cultured cells and animal-derived tissues.