Human Canalicular multispecific organic anion transporter 2 (ABCC3) ELISA Kit

A Sandwich ELISA from Assay Genie for the quantitative detection of human Canalicular multispecific organic anion transporter 2 (ABCC3), also known as Multidrug resistance-associated protein 3 (MRP3), in human samples. The assay uses a colorimetric detection method and is intended for research use only.

ABCC3 is a multi-pass membrane protein that may act as an inducible transporter in the biliary and intestinal excretion of organic anions, serving as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes. Dysregulation of ABCC3 has been implicated in liver disease, cancer, and drug resistance, highlighting its significance as a biomarker and potential therapeutic target.

The kit offers a detection range of 78-5000pg/mL and a sensitivity of 21pg/mL. It is compatible with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, with specificity for natural and recombinant human ABCC3. Listed research area: cardiovascular.