Human Cadherin EGF LAG Seven Pass G-Type Receptor 2 (CELSR2) ELISA Kit

Quantitative immunoassay for human CELSR2 protein offered in a 96 assay configuration by Assay Genie. CELSR2 belongs to the flamingo subfamily of atypical cadherins, distinguished by its seven-pass transmembrane topology paired with extracellular EGF-like and Laminin-G domains. The receptor participates in planar cell polarity, oriented cell division during neural tube closure, and maintenance of blood-brain barrier function. Genomic variants at the 1p13.3 locus have been linked to LDL cholesterol levels and coronary artery disease susceptibility in population studies.

The kit accepts tissue homogenate preparations and supports research use only applications in vascular biology, neuroscience, and lipid metabolism research. Each kit provides reagents for 96 individual determinations, suitable for standard curve construction and replicate analysis across experimental conditions. Researchers can apply the kit to in vitro workflows measuring CELSR2 abundance in primary tissue lysates and cell line models where planar cell polarity, ciliogenesis, or adhesion signaling is under investigation.