Human C4 Binding Protein Alpha (C4BPa) ELISA Kit

Assay Genie offers a quantitative immunoassay for measuring C4 Binding Protein Alpha (C4BPa), a key regulator of the classical complement cascade that controls C4-mediated opsonization and immune complex clearance. Circulating C4BPa exists predominantly as a multimeric disulfide-linked glycoprotein that binds C4b and limits downstream complement activation, making its quantification valuable in studies of innate immunity, autoimmune disease, and complement-mediated inflammation. Researchers investigating conditions such as systemic lupus erythematosus, rheumatoid arthritis, venous thrombosis, or recurrent infections frequently monitor C4BPa levels to understand disease mechanisms and patient phenotypes. This kit is supplied as a complete reagent set intended for in vitro research use only, supporting absorbance-based measurement in a standard microplate workflow across a 96-assay plate size suitable for moderate-throughput screening. The assay is configured for human samples, allowing laboratories to profile C4BPa concentrations in serum-derived and plasma-derived specimens obtained from clinical cohorts or experimental models. Each kit includes pre-coated plates, calibrated standards, detection antibody, and the buffers required for routine laboratory operation, with all components shipped ready for use under standard refrigerated storage conditions. Compatible with standard plate readers, the assay produces absorbance data that can be analyzed against a generated standard curve for accurate concentration determination.