Human C-C motif chemokine 21 (CCL21) ELISA Kit

Assay Genie offers a Sandwich ELISA Kit for the quantitative measurement of human C-C motif chemokine 21 (CCL21) in research samples. The assay is validated for use with serum and plasma and is intended for research use only.

According to the manufacturer's specifications, the kit provides a detection range of 78-5000 pg/mL and a sensitivity of 40.7 pg/mL. Reported precision values include an intra-assay CV of 7.2% and an inter-assay CV of 10.8%. Linearity has been assessed in serum, EDTA plasma and heparin plasma across multiple dilution factors.

CCL21 is a chemokine that inhibits hemopoiesis and stimulates chemotaxis, showing preferential activity toward naive T-cells. It may play a role in mediating homing of lymphocytes to secondary lymphoid organs, binds CCR7 as a monomer, and interacts with atypical chemokine receptor ACKR4. Researchers can use this kit to study immune responses, cell migration and inflammation, including conditions such as autoimmune diseases, allergies and inflammatory disorders.