Human C-C motif chemokine 20 (CCL20) ELISA Kit

Designed by Assay Genie for the quantitative measurement of human C-C motif chemokine 20 (CCL20), this sandwich-format ELISA kit uses a colorimetric detection method and is reactive with human samples. Validated sample types include serum and plasma, with the manufacturer also listing tissue homogenates, cell culture supernatants and other biological fluids as additional compatible matrices. Specificity is confirmed for both natural and recombinant human C-C motif chemokine 20, and the associated UniProt reference is P78556.

CCL20, also referred to as macrophage inflammatory protein-3 alpha (MIP-3α) and liver and activation-regulated chemokine, is a secreted chemokine that signals through the CCR6 receptor. It mediates the chemotaxis of dendritic cells, effector/memory T-cells and B-cells and is implicated in inflammatory and autoimmune processes as well as in cancer pathology, making it a relevant marker for immunology and inflammation research.

Key performance figures reported by the manufacturer include a detection range of 7.8-500 pg/mL, a sensitivity of 3.5 pg/mL, an intra-assay CV of 4.6% and an inter-assay CV of 7.8%. Recovery in serum is reported as an average of 101% (range 95-107%) and in plasma as an average of 103% (range 97-109%). The product is intended for research use only.