Human C-C chemokine receptor type 3 (CCR3) ELISA Kit

The Assay Genie sandwich ELISA kit provides a reliable tool for the precise measurement of human C-C chemokine receptor type 3 (CCR3) levels in serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Using a colorimetric ELISA detection method, the kit offers specificity for both natural and recombinant human CCR3 and is intended for research use only.

Quantitative performance includes a detection range of 0.312-20ng/mL and a sensitivity of 0.078ng/mL. Reported precision values are an intra-assay CV of 4.6% and an inter-assay CV of 7.6%. Linearity has been validated in serum, EDTA plasma, and heparin plasma across serial dilutions (1:2, 1:4, 1:8, 1:16), with serum recovery averaging 99% (range 93-105%) and plasma recovery averaging 101% (range 95-107%).

CCR3 is a G-protein coupled receptor central to immune regulation, particularly eosinophil migration and activation, with dysregulation linked to inflammatory conditions such as asthma, allergic diseases, and autoimmune disorders. The receptor is also known by the synonyms eosinophil eotaxin receptor, CD193, C-C CKR-3, and CMKBR3, and is catalogued under UniProt P51677, making this kit a useful resource for immunology research into disease pathogenesis and potential therapeutic interventions.