Human Bone Morphogenetic Protein Receptor 1A (BMPR1A) ELISA Kit

BMPR1A (Bone Morphogenetic Protein Receptor 1A) is a type I serine/threonine kinase receptor that mediates signaling through BMP2, BMP4, BMP7, and GDF5 ligands, activating SMAD1/5/9 pathways to regulate osteogenesis, chondrogenesis, and stem cell differentiation. This Assay Genie kit quantifies BMPR1A protein in tissue homogenates and cell lysates, supporting investigation of juvenile polyposis syndrome, hereditary hemorrhagic telangiectasia, and bone morphogenetic protein signaling cascades. The microplate-based configuration uses a capture antibody specific to human BMPR1A, with a sample volume of approximately 50 uL per well. For research use only, the kit should be stored refrigerated and protected from light, with standard solutions aliquoted to limit freeze-thaw cycles. No significant cross-reactivity is observed with BMPR1B or other TGF-beta superfamily receptors, ensuring specific detection of the target analyte.