Human Bone morphogenetic protein 7 (BMP7) ELISA Kit

Manufactured by Assay Genie, this sandwich ELISA kit is designed for the quantitative detection of human Bone Morphogenetic Protein 7 (BMP-7) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. BMP-7 is described as a key regulator of bone formation with roles in skeletal development and repair, and it also has important functions in the kidneys and heart, making it a valuable biomarker for research into osteoporosis, kidney disorders, and cardiovascular diseases.

The assay has a detection range of 31.2-2000pg/mL and a sensitivity of 10pg/mL. Intra-assay CV is 4.3% and inter-assay CV is 6.5%. The kit is specific for natural and recombinant human BMP-7 and is intended for research use only, with research area listed as cancer. BMP-7 is a secreted homodimer (disulfide-linked) that induces cartilage and bone formation and plays a role in calcium regulation and bone homeostasis.

Recovery is 80% (range 80-85%) for serum and 81% (range 80-87%) for plasma. Linearity across 1:2 to 1:16 dilutions spans 86-117% in serum, 90-116% in EDTA plasma, and 87-115% in heparin plasma.